{"id":11361,"date":"2024-11-11T06:00:27","date_gmt":"2024-11-11T05:00:27","guid":{"rendered":"https:\/\/blogs.bmj.com\/bjsm\/?p=11361"},"modified":"2024-10-26T16:45:42","modified_gmt":"2024-10-26T15:45:42","slug":"sport-practice-and-its-effects-on-aortic-size-and-valve-function-in-bicuspid-aortic-valve-disease-cross-sectional-report-from-the-spread-study","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/bjsm\/2024\/11\/11\/sport-practice-and-its-effects-on-aortic-size-and-valve-function-in-bicuspid-aortic-valve-disease-cross-sectional-report-from-the-spread-study\/","title":{"rendered":"Sport PRactice and its Effects on aortic size and valve function in bicuspid Aortic valve Disease: cross-sectional report from the SPREAD study"},"content":{"rendered":"<p><strong>Key words:<\/strong> Bicuspid aortic valve; athletes; valvulo-aortopathy<\/p>\n<p><strong>Why is this study important?<\/strong><br \/>\nBicuspid aortic valve (BAV) is the most common congenital heart valve disease in the general\u00a0population, including young athletes. BAV is considered a significant valvulo-aortopathy because\u00a0BAV patients may experience worsening valve function as well as aortic dilatation and decreased\u00a0aortic elasticity, which can increase the risk of aortic dissection. Multiple factors influence the\u00a0progression of these complications in BAV patients, and the role of sports activity in this\u00a0progression remains unclear. Intense physical activity might exacerbate the condition, leading to a\u00a0higher risk of worsening valve function and aortic dissection or rupture. However, the existing\u00a0studies are few and have small sample sizes. To address this gap, we conducted an international\u00a0multi-center study comparing competitive athletes with BAV to non-athletes with BAV and\u00a0competitive athletes with normal valve (TAV) to determine whether these populations differ\u00a0regarding aortic size and valve function (1).<\/p>\n<p><strong>How did the study go about this?<\/strong><\/p>\n<p>The first phase of the project involved a cross-sectional study designed to assess valve function\u00a0and ascending aortic dimensions and establish the prevalence of aortic dilatation and aortic\u00a0regurgitation or stenosis in athletes with BAV, compared to athletes with TAV and non-athletes\u00a0with BAV. Echocardiography was used to evaluate valve function, aortic size, and bi-ventricular\u00a0measurements.<\/p>\n<p><strong>What did the study find?<\/strong><\/p>\n<p>Competitive athletes with BAV had similar aortic dimensions to non-athletes with BAV but larger\u00a0than athletes with TAV, demonstrating no differences in aortic dimensions between athletes and\u00a0non-athletes with BAV. Additionally, both athletes and non-athletes with BAV showed a higher\u00a0mean gradient and a greater occurrence of mild stenosis or regurgitation compared to TAV\u00a0athletes. However, there were no significant differences within the BAV groups. Notably, athletes\u00a0with BAV had larger left ventricular volumes and mass compared to both TAV athletes and non-athletes with BAV, suggesting a distinct pattern of left ventricular re-modelling in BAV athletes.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone  wp-image-11363\" src=\"https:\/\/blogs.bmj.com\/bjsm\/files\/2024\/11\/SPREAD-figure-300x186.jpg\" alt=\"\" width=\"390\" height=\"242\" srcset=\"https:\/\/blogs.bmj.com\/bjsm\/files\/2024\/11\/SPREAD-figure-300x186.jpg 300w, https:\/\/blogs.bmj.com\/bjsm\/files\/2024\/11\/SPREAD-figure.jpg 512w\" sizes=\"auto, (max-width: 390px) 100vw, 390px\" \/><\/p>\n<p><strong>What are the key take-home points?<\/strong><\/p>\n<p>These results suggest that competitive athletes with BAV are not significantly different from non-athletes with BAV. However, given the greater left ventricular remodelling, larger aortic diameters,\u00a0and worse aortic valve function observed in BAV individuals compared to athletes with TAV, close,\u00a0longitudinal follow-up is necessary.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone  wp-image-11364\" src=\"https:\/\/blogs.bmj.com\/bjsm\/files\/2024\/11\/Infographic-Sport-PRactice-and-its-Effects-on-aortic-size-and-valve-function-in-bicuspid-Aortic-valve-Disease-300x300.png\" alt=\"\" width=\"533\" height=\"533\" srcset=\"https:\/\/blogs.bmj.com\/bjsm\/files\/2024\/11\/Infographic-Sport-PRactice-and-its-Effects-on-aortic-size-and-valve-function-in-bicuspid-Aortic-valve-Disease-300x300.png 300w, https:\/\/blogs.bmj.com\/bjsm\/files\/2024\/11\/Infographic-Sport-PRactice-and-its-Effects-on-aortic-size-and-valve-function-in-bicuspid-Aortic-valve-Disease-150x150.png 150w, https:\/\/blogs.bmj.com\/bjsm\/files\/2024\/11\/Infographic-Sport-PRactice-and-its-Effects-on-aortic-size-and-valve-function-in-bicuspid-Aortic-valve-Disease-768x768.png 768w, https:\/\/blogs.bmj.com\/bjsm\/files\/2024\/11\/Infographic-Sport-PRactice-and-its-Effects-on-aortic-size-and-valve-function-in-bicuspid-Aortic-valve-Disease-640x640.png 640w, https:\/\/blogs.bmj.com\/bjsm\/files\/2024\/11\/Infographic-Sport-PRactice-and-its-Effects-on-aortic-size-and-valve-function-in-bicuspid-Aortic-valve-Disease.png 1080w\" sizes=\"auto, (max-width: 533px) 100vw, 533px\" \/><\/p>\n<p><strong>Authors<\/strong>: Flavio D\u2019Ascenzi, MD, PhD; Luna Cavigli, MD, PhD. Department of Medical\u00a0Biotechnologies, Sports Cardiology and Rehab Unit, University of Siena, Siena, Italy<\/p>\n<p><strong>References<\/strong>:<\/p>\n<ol>\n<li>D&#8217;Ascenzi F, Cavigli L, Cameli M, et alSport PRactice and its Effects on aortic size and valve\u00a0function in bicuspid Aortic valve Disease: a cross-sectional report from the SPREAD\u00a0study British Journal of Sports Medicine Published Online First: 16 August 2024. doi:10.1136\/bjsports-2023-107772<\/li>\n<\/ol>\n<p><!--TrendMD v2.4.8--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Key words: Bicuspid aortic valve; athletes; valvulo-aortopathy Why is this study important? Bicuspid aortic valve (BAV) is the most common congenital heart valve disease in the general\u00a0population, including young athletes. BAV is considered a significant valvulo-aortopathy because\u00a0BAV patients may experience worsening valve function as well as aortic dilatation and decreased\u00a0aortic elasticity, which can increase the [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/blogs.bmj.com\/bjsm\/2024\/11\/11\/sport-practice-and-its-effects-on-aortic-size-and-valve-function-in-bicuspid-aortic-valve-disease-cross-sectional-report-from-the-spread-study\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":463,"featured_media":11364,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[16343,16068,16228,8311],"class_list":["post-11361","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized","tag-aortic-valve-disease","tag-featured","tag-heart-muscle","tag-valvular-heart-disease"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Sport PRactice and its Effects on aortic size and valve function in bicuspid Aortic valve Disease: cross-sectional report from the SPREAD study - BJSM blog - social media&#039;s leading SEM voice<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/bjsm\/?p=11361\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Sport PRactice and its Effects on aortic size and valve function in bicuspid Aortic valve Disease: cross-sectional report from the SPREAD study - BJSM blog - social media&#039;s leading SEM voice\" \/>\n<meta property=\"og:description\" content=\"Key words: Bicuspid aortic valve; athletes; valvulo-aortopathy Why is this study important? 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