Temozolomide reduces risk of seizures in low grade glioma!

Posted on by Steve Vucic, Web Editor

Low grade gliomas are associated with a higher frequency of seizures.  While antieplipetic medications are utilized to reduced seizure frequency, in this issue of JNNP temozolomide was also associated with a a significant reduction in seizure frequency.  Perhaps temozolomide should be added to therapy of LGGs with intractable seizures.

 

Read more at http://jnnp.bmj.com/content/86/4/366.abstract

 

Seizure reduction in a low-grade glioma: more than a beneficial side effect of temozolomide

  1. Johan A F Koekkoek1,2,
  2. Linda Dirven1,
  3. Jan J Heimans1,
  4. Tjeerd J Postma1,
  5. Maaike J Vos2,
  6. Jaap C Reijneveld1,
  7. Martin J B Taphoorn1,2
    J Neurol Neurosurg Psychiatry 2015;86:366-373 doi:10.1136/jnnp-2014-308136

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