Cholinesterase inhibitors (ChIs) improve cholinergic transmission and thereby may lead to improved cognitive function in PD, although the risk of side-effects such as falls may be potentially increased. In an upcoming issue of JNNP (On line first) Pagano and colleagues conducted a meta-analysis to further assess these issues. The results show a clear improvement of cognitive function in PD, without an increase in risk of falls, although the risk of tremor and adverse drug reactions was increased.
Read more at: http://jnnp.bmj.com/content/early/2014/09/15/jnnp-2014-308764.abstract
J Neurol Neurosurg Psychiatry doi:10.1136/jnnp-2014-308764
- Movement disorders
- Research paper
Cholinesterase inhibitors for Parkinson’s disease: a systematic review and meta-analysis
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