An education

Over the last few decades, there have been unprecedented advances in our capacity to treat medical disorders. Neurological disease in particular has made significant strides. While a cure may still be beyond our reach in many conditions, we are able to reduce suffering and improve quality of life in a way that would have been […]

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Factors governing progression in MS: Something old, something frequent!

The holy grail of MS therpay is to prevent the onset of the debilitating MS phase.  All of the current therpaies are aimed at preventing such developments, and more importantly early treatment with immunomodulatory therapies was shown to be more efficacious at preventing disability development.   The issue of whether multiple relapses or “attacks” govern diability […]

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Relapses in multiple sclerosis. It’s all in the brain!

Acute neurological deficits, otherwise known as relapses, characterise relapsing-remitting forms of MS.  A high annualised relapse rate is associated with disability development in the future, and current therapeutic endeavours are aimed at reducing such relapses.  Clinically, relapses are typically represented by sensorimotor deficits, gait unsteadiness, optic neuritis etc.  While cognitive decline and worsening fatigue may […]

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Psychogenic disorders and persistent disability?

Psychogenic motor disorders may be frequently encountered in “organic” neurology, especially in the world of movement disorders.  This group of disorders needs to be distinguished from malingering as the patients really feel that they have a functional deficits even though neurology can not explain the site and origins of deficits.  Indeed, transcranial magnetic stimulation studies […]

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