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Does good glycaemic control benefit children after cardiac surgery?

8 Nov, 12 | by Alistair Lindsay

The benefit of tight glycaemic control in the post-operative setting has come under increasing scrutiny of late. Initial small scale studies suggesting large clinical benefits have been followed by much larger multi-centre trials demonstrating neutral or even harmful effects of tight blood sugar control, with most investigators pointing towards the high occurrence of hypoglycaemia as being the main problem associated with therapy. These studies have been almost exclusively in adults but the role of tight glycaemic in critically ill children is less well understood. In this study, Agus et al examined whether tight glycaemic control reduces morbidity after paediatric cardiac surgery. more…

Glucose-Insulin-Potassium shows some benefit in acute coronary syndrome

6 Jul, 12 | by Alistair Lindsay

Intravenous glucose-insulin-potassium (GIK) is postulated to be beneficial in acute ischaemic syndromes via two mechanisms: by providing metabolic support to ischaemic myocardium, and by preventing arrhythmias and cardiac arrest due to ischaemia-related metabolic derangements.  Importantly, these benefits are most likely to be seen if GIK is started as soon as possible after the onset of myocardial ischaemia, therefore GIK should ideally be initiated in the out-of-hospital setting. more…

Normalisation of blood glucose levels following myocardial infarction predicts favourable in hospital outcome.

21 Jun, 09 | by Alistair Lindsay

Despite a strong association between elevated blood glucose levels and increased rates of mortality among patients hospitalised with acute myocardial infarction (AMI), the benefit of acutely lowering levels of blood glucose remains controversial. Several questions remain unanswered: more…

Fasting blood glucose levels identify high-risk individuals across the ACS spectrum

15 Apr, 09 | by Alistair Lindsay

Elevated blood glucose at hospital admission, and elevated fasting blood glucose levels during admission, have been shown to predict worse outcome among patients with STEMI, however, the contribution of glucose levels to risk predictive algorithms involving patients with acute coronary syndromes (ACS) remains unclear. more…

Fasting blood glucose levels identify high-risk individuals across the ACS spectrum

14 Apr, 09 | by Alistair Lindsay

Elevated blood glucose at hospital admission, and elevated fasting blood glucose levels during admission, have been shown to predict worse outcome among patients with STEMI, however, the contribution of glucose levels to risk predictive algorithms involving patients with acute coronary syndromes (ACS) remains unclear. more…

Highlighted articles from non-cardiological journals relevant to cardiology.

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