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Archive for February 24th, 2012

Statins inhibit thrombosis

24 Feb, 12 | by Alistair Lindsay

Hypercholesterolemia is one of the primary risk factors for atherosclerotic coronary disease. Statins have revolutionised lipid management with their proven ability to reduce circulating cholesterol levels and have even demonstrated regression of coronary plaques. Interestingly, statins have also been shown to have anti-inflammatory and anti-thrombotic activities, with several studies having shown statin therapy to be associated with a significant reduction in venous thromboembolism.  However, the mechanisms by which statins achieve this remain obscure. more…

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