Alveolar Ethmoidal Rhabdomyosarcoma in a Young Adult Male

A very well written case, which would be of interest to many specialties, with a clear discussion and relevant references. It may be useful for readers to highlight that rhabdomyosarcoma is most common in the paediatric population and thereby making the  presentation of this type of tumour in this case more unusual. Also mention of the reasoning behind […]

Read More…

An Unusual Posterior Fossa Tumour in a Young Child

The authors describe the case of a 23-month old child with a posterior fossa tumour, which was removed and turned out to be a choroid plexus papilloma. As they state, choroid plexus papilloma is encountered commonly in the first two years of life, but very rarely in the posterior fossa. It is more common in […]

Read More…

Chiari malformation and central sleep apnoea: successful therapy with adaptive pressure support servo-ventilation following surgical treatment

This is a well written manuscript. The case is of interest to general physicians and highlights an important associations. The therapy described is of innovative nature and allows the reader to be familiarized with this novel mode of therapy. The case also discusses important, to general physicians, Chiari malformation. In my opinion this is a […]

Read More…

Three cases of severely disseminated Staphylococcus aureus infection in patients treated with tocilizumab

These cases illustrate a number of important points of relevance to acute and general medical physicians as well as in specialties such as Rheumatology. Firstly, patients who are on anti-IL-6 medications may present in a different and less florid way when infected systemically with Staphylococcus aureus than immunocompetent patients. Secondly, they provide a reminder to […]

Read More…

Hypertrophic Pulmonary Osteoarthropathy and Congenital Heart Disease

Secondary Hypertrophic osteoarthropathy in cyanotic congenital heart disease is a well known complication but its awareness is coming down. Though its prevalence may have come down thanks to total correction and better palliation during childhood it has not totally disappeared. Awareness about its presentation and x-ray findings is must for a timely diagnosis and management […]

Read More…

Failure of anti-TNF therapy to reactivate previously septic prosthetic joints

There are many problems and alarms arising from anti-TNF therapy employed by biological drugs and infections. On the other hand, the medical behavior on this issue is usually personal and medical decisions are made on a case-by-case.  In this case, the elapsed time from the previous infections is really considerable and it is also reasonable […]

Read More…

Bilateral cataracts and insulin oedema in a child with type 1 diabetes mellitus

Well written case report of insulin edema and cataract following intense insulin. The only similar case is by Juliusson[1] but in this latter case cataract was present initially and insulin edema followed insulin therapy. The current case report offers good discussion allowing students to learn about the pathophysiology of cataract and insulin edema. This unique […]

Read More…

Vulvar adenocarcinoma: the visual resemblance with a vulvar abscess

Though vulvar cancer is not very common, the misdiagnosis of malignancy as an abscess by practising gynaecologists is a mistake, which can prove costly to the patient. This article focuses attention on this aspect. Reviewer Ranganath Ratnagiri Yashoda Cancer Institute Vulvar adenocarcinoma: the visual resemblance with a vulvar abscess […]

Read More…

Variable ECG findings associated with pulmonary embolism

Very interesting case and well written. One could postulate that the hypoxia associated with massive PE might have caused ischaemic changes without infarction or that the death was too soon for changes of infarction to be visible at post mortem examination. Either way, a good learning point, though clearly thrombolysis for either PE or MI […]

Read More…