Three cases of severely disseminated Staphylococcus aureus infection in patients treated with tocilizumab

These cases illustrate a number of important points of relevance to acute and general medical physicians as well as in specialties such as Rheumatology. Firstly, patients who are on anti-IL-6 medications may present in a different and less florid way when infected systemically with Staphylococcus aureus than immunocompetent patients. Secondly, they provide a reminder to […]

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Hypertrophic Pulmonary Osteoarthropathy and Congenital Heart Disease

Secondary Hypertrophic osteoarthropathy in cyanotic congenital heart disease is a well known complication but its awareness is coming down. Though its prevalence may have come down thanks to total correction and better palliation during childhood it has not totally disappeared. Awareness about its presentation and x-ray findings is must for a timely diagnosis and management […]

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Failure of anti-TNF therapy to reactivate previously septic prosthetic joints

There are many problems and alarms arising from anti-TNF therapy employed by biological drugs and infections. On the other hand, the medical behavior on this issue is usually personal and medical decisions are made on a case-by-case. ┬áIn this case, the elapsed time from the previous infections is really considerable and it is also reasonable […]

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