My list of medical anniversaries in 2018 is restricted to those that are multiples of 50 years. Thus, I have not included, for example, the 40th anniversary of the first test tube baby, Louise Brown; nor the 40th anniversary of the poisoning, supposedly with ricin, of Georgi Markov; nor the 60th anniversary of Ian Donald’s description of the diagnostic use of ultrasound; nor the 70th anniversary of the National Health Service Acts; nor the 90th anniversary of the 1928 Amendments to the 1925 Dangerous Drugs Act, which made cannabis illegal; nor the 175th anniversary of the killing of the Prime Minister’s private secretary, Edward Drummond, in Whitehall by Daniel M’Naghten.
The anniversary list does include the following topics:
- chemistry (discovery of strychnine and ergotamine);
- therapeutics and toxicology (blood transfusion; the Chicago poisonings with antimony potassium tartrate, tartar emetic);
- infectious diseases (the Picardy sweat; the Spanish flu; discovery of Leptospira icteroides);
- new institutions (the Royal College of Physicians; Merck & Co; the City Chair of Materia Medica and Department of Materia Medica in the University of Edinburgh);
- new publications (Pharmacopoeia Londinensis; Cancer Ward).
Words also have anniversaries. Listed at the end are words whose earliest recorded instances, as given in the Oxford English Dictionary (OED), have anniversaries this year. For example, the term “angina pectoris” was first used by William Heberden in a lecture, “Some Account of a Disorder of the Breast”, given at the Royal College of Physicians on 21 July 1768 and published in the Medical Transactions of the College in 1772 (pictured below). Heberden’s wording suggests that he coined the term. Earlier examples (antedatings) are highly unlikely.
However, the OED, thorough though it is, does not always list the very earliest uses of words, and antedatings can sometimes be discovered. For example, the earliest instance of “chickenpox” listed in the first (1889) and second (1989) editions of the OED was from editions of William Chambers’ Cyclopedia, dated 1727–1738. In 2000, searching for something else, I found a much earlier instance, in Richard Morton’s Puretologia or Exercitatio de Febribus Inflammatoriis (1694): “… quod Variolae istae (quod primo monui) erant maximae Benignae eae scil. quae vulgo dicuntur Chicken-Pox”, an instance of an English word used in a Latin text. Since then, the lexicographers have unearthed an even earlier instance, now included in the online edition of the OED (updated December 2012), from Mercurius Politicus (1658). Even earlier instances may be there to be discovered.
Anniversary words concerned with words include:
- perfluence (1568), a flow of words, logorrhoea;
- word-mongering (1768), first recorded in a letter written by Laurence Sterne, discussing his definition of the word “blockhead” (pictures);
- spuria (1918), spurious works, words, etc.
None of any of those here, I hope.
Some medical anniversaries in 2018
Foundation of the Royal College of Physicians of London by Henry VIII; the founding charter was signed on 23 September; the first President was Thomas Linacre (1460–1524)
Publication of the Pharmacopoeia Londinensis; it was translated into English by Nicholas Culpeper in 1649
Merck & Co founded by Friedrich Jacob Merck in the Engelapotheke in Darmstadt, Germany
First appearance of the Picardy sweat, suggested to have been due to hantavirus
Foundation of the the City Chair of Materia Medica and Department of Materia Medica in the University of Edinburgh, under Professor Francis Home
William Heberden coins the term “angina pectoris” in a lecture at the Royal College of Physicians
James Blundell (1790–1878) describes blood transfusion
Discovery of strychnine by Pierre-Joseph Pelletier (1788–1842) and Joseph Bienaimé Caventou (1795–1877) in the Saint Ignatius bean (Strychnos ignatia) and Strychnos nux vomica
Pandemic of influenza, the so called “Spanish flu” (Photocredit: Cynthia Goldsmith; Content Providers(s): CDC/ Dr. Terrence Tumpey/ Cynthia Goldsmith)
The Chicago restaurant poisonings, in which customers who tipped poorly were given antimony potassium tartrate (tartar emetic) in their food or drink; the mixture was called a Mickey Finn
Isolation of ergotamine from Claviceps purpurea by Arthur Stoll at Sandoz
Hideyo Noguchi discovers the spirochaete Leptospira icteroides and incorrectly believes it to be the cause of yellow fever
The 1967 Abortion Act takes effect
Publication of Cancer Ward by Alexander Solzhenitsyn (born 1918)
The Nobel Prize in Physiology or Medicine awarded to (from left to right) Robert W Holley, Har Gobind Khorana, and Marshall W Nirenberg “for their interpretation of the genetic code and its function in protein synthesis”
Lexicographic anniversaries in 2018 (numbers in parentheses are the total numbers of new words in the indicated years)
1568 (400): kinkcough (whooping cough)
pillock (the penis)
1618 (345): pharmacopaea [sic]
pharmacopaean (a physician knowledgeable about drugs or skilled in pharmacy)
1668 (399): bismuth
1718 (152): bunion
1768 (268): angina pectoris
1818 (640) : ante-mortem
mania a potu (delirium tremens)
1868 (912): acneform
Graves’s disease [sic]
1918 (372): anorchidism
X disease (Murray Valley encephalitis)
1968 (419): aerobics
Jeffrey Aronson is a clinical pharmacologist, working in the Centre for Evidence Based Medicine in Oxford’s Nuffield Department of Primary Care Health Sciences. He is also president emeritus of the British Pharmacological Society.
Competing interests: None declared.