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Archive for April, 2007

NEJM 12 Apr 2007

16 Apr, 07 | by BMJ Group

A big prospective North American trial – COURAGE - confirms the message of the BMJ a fortnight ago: for chronic stable angina, percutaneous coronary intervention offers no advantage over optimal medical therapy. more…

BMJ 14 Apr 2007

16 Apr, 07 | by BMJ Group

786 Several years ago, Philip Poole-Wilson issued a warning that too many cardiovascular trials use composite end-points and that this can seriously distort their conclusions. more…

Lancet 14 Apr 2007

16 Apr, 07 | by BMJ Group

Another very promising new drug for HIV has arrived – the HIV-1 integrase inhibitor raltegravir. It produced good results in this phase II trial in multi-drug resistant patients and β€œthe safety profile of raltegravir is comparable with that of placebo at all doses studied.

Arch Intern Med 9 Apr 2007

16 Apr, 07 | by BMJ Group

The fashion for chocolate-drinking in England faded more than two hundred years ago, to be replaced largely by tea more…

Fungus of the Week: Morchella esculenta

16 Apr, 07 | by BMJ Group

These vernal delicacies tend to grow where you can least easily spot them – on burnt ground, in grass around old apple trees, or amongst bark and wood chips used to mulch flower beds. more…

Remedy UK to pursue legal action

10 Apr, 07 | by BMJ Group

Remedy UK, the organisation behind the protest marches against MTAS, has decided it will continue its legal action — despite the latest compromise proposals aimed at ensuring appointments can be made in time for August, when posts become vacant.

more…

JAMA 4 Apr 2007

10 Apr, 07 | by BMJ Group

This Japanese study breaks new ground in attempting to establish the prevalence of neuraminidase resistance in influenza B viruses. At present it is low, but of course selection pressure could change all that if these drugs were widely used in an epidemic. more…

NEJM 5 Apr 2007

10 Apr, 07 | by BMJ Group

If, as Michael Baum states, you have to screen 1,000 women with mammography for ten years to save one death from breast cancer, is computer-aided detection going to transform the scene? more…

BMJ 7 Apr 2007

10 Apr, 07 | by BMJ Group

In England, we are lucky to have our screening programmes presided over by a sceptical Scot (Muir Gray) who is alert to the dangers of screening. Nevertheless, argues Nicola Law here, we are in the process of adopting a policy for opportunistic Chlamydia screening in young women based on evidence that is contradictory and frequently misrepresented. more…

Lancet 7 Apr 2007

10 Apr, 07 | by BMJ Group

Just after the editorials comes a short clinical update on essential tremor which usefully summarises the clinical features and how to distinguish this from other tremulous disorders. When it comes to treatment, however, the evidence is generally shaky. more…

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