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CF

Q: Echogenic bowels and new babies

31 Jan, 10 | by Bob Phillips

Bias plotIt was a vogue around the start of regular antenatal ultrasound scanning to note everything, associate wildly and some up with ‘antenatal markers of disease’, as I recollect. Some of these things turned out to be quite useful (nose bones, for instance, or their absence) and others still confuse me … like the ‘echogenic focus of bowel’ more…

Q: Is an OGTT good enough for CF diabetes testing?

23 Jul, 08 | by Bob Phillips

Glucose Tolerance DrinkJamie, a 13-year-old girl with cystic fibrosis (CF), has been referred to the Paediatric Diabetes clinic because of an abnormal oral glucose tolerance test (OGTT) in her recent CF Annual Review. It showed impaired glucose tolerance. Continuous glucose monitoring system (CGMS) over three days showed normal fasting and pre-prandial glucose but frequent post-prandial glucose excursions between 11.1 mmol/l and 16.0 mmol/l. In retrospect, although Jamie‚Äôs previous OGTT carried out at Annual Review were normal, her lung function had gradually deteriorated over the past three years. This had been attributed to increasing episodes of infective exacerbations. You wondered for how long Jamie has had abnormal glucose metabolism which had gone undetected in her previous OGTT. more…

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