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Pharmacology

Voriconazole plasma levels

5 Feb, 08 | by Ian Wacogne

In a case series of 5 children receiving voriconazole, highly variable plasma levels were observed with recommended dosing regimes, implying that plasma monitoring may be necessary in children.  Here.

Growth Hormone

21 Jan, 08 | by Ian Wacogne

Perspective: Petrou and McIntosh look at the methods of improving concordance with growth hormone therapy. Here.

Safe Prescribing

21 Jan, 08 | by Ian Wacogne

Perspective:  Sammons and Conroy look at ways of improving safety of prescribing for children.  Here.

Growth Hormone

21 Jan, 08 | by Ian Wacogne

In a study using a technique called conjoint analysis, which looks at consumer choices, a series of families were able to make choices about the device required to deliver growth hormone.  Here.

Reducing prescribing errors

20 Jan, 08 | by Ian Wacogne

In response to a postal questionnaire, few centres have a systematic approach to assessing competency of paediatric prescribers; a literature review goes on to describe that there are no validated tools, nor has there been any evaluation of the impact of teaching on prescribing.  Here.

Antipyretics

8 Oct, 07 | by Ian Wacogne

In a survey of 181 parents attending a clinic, there was widespread confusion about the correct use of antipyretics.  Here.

Asthma

5 Sep, 07 | by Ian Wacogne

With reference to prescription rates, the introduction of the BTS asthma guidelines has resulted in a fall in the amount of syrups prescribed - although there were still 121,000 presciptions in 2006.  There remains a higher amount of combination steroid/long acting beta-agonist inhaler prescription than would be expected.  Here.

Growth Hormone

5 Sep, 07 | by Ian Wacogne

By assessing general practitioner prescriptions, of 75 children on Growth Hormone, 23% missed more than 2 injections per week, with factors such as short duration on growth hormone being associated with poorer concordance.  Here.

Fatal adverse drug reactions

11 Jul, 07 | by BMJ Group

A BSPU (British Surveillance) study identified 7 deaths in a 13 months period. When assessed by an expert panel, five deaths were thought unlikely to be medication related, and for the remaining two a consensus could not be reached. Here.

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