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October 2007 Issue

9 Oct, 07 | by Ian Wacogne

This post collects together the precis of the major articles – perspectives, leading articles and original articles – in the October 2007 issue.


Cystic Fibrosis

Doull looks at the ongoing management of cystic fibrosis, and makes suggestions about monitoring of children with it. Here.

Child Protection

Stephenson reviews the recent legal rulings that the duty of care owed by a paediatrician is to the child ahead of other considerations. Here.

Leading Articles

Clinical Research

Smyth looks at the top ten most important trials in children, and reflects on what this means for future research into childhood disease. Here.

Conduct disorder

Keen looks at newer approaches to the management of conduct disorder, following on from the Child in Mind project. Here.

Original articles

Cystic Fibrosis

In analysis of 315 children diagnosed with cystic fibrosis at one week via screening, a subgroup with severe mutations developed pancreatic insufficiency over time. Here.


With reference to prescription rates, the introduction of the BTS asthma guidelines has resulted in a fall in the amount of syrups prescribed – although there were still 121,000 presciptions in 2006. There remains a higher amount of combination steroid/long acting beta-agonist inhaler prescription than would be expected. Here.

Infant feeding

Of 928 children in the ALSPAC cohort, 22.7% were anaemic by 8 months and 18.1% at 12 months, associated with excess milk feeding. Here.

Quality of Life

In a study of 1238 UK children, some in good health and some with chronic disease, the Manchester-Minneapolis tool was a valid measure of QoL. Here.


A short questionnaire on environmental factors and symptoms in Swiss children with asthma had good repeatability. Here.


817 New Zealand children of European ancestry were followed from birth in a longitudinal study which suggests that factors for obesity are established in the preschool period. Here.


DXA analysis of body fat in 1251 children suggests that gender and ethnicity have an impact which is not reflected by BMI analysis. Here.


Comparing the BMI of triads of mother, father and child at 7.5 years for 4,654 children in the ALSPAC cohort shows that maternal BMI is no more closely associated with child BMI than paternal is BMI – suggesting that there has been no effect of interuterine programming. Here


In a cohort of 2869 children, birth weight did not predict allergic disease, but increased birth length may predict lower risk of late childhood wheeze. Here.

Nephrotic Syndrome

In a series of 52 children with 162 relapses of nephrotic syndrome, there was no association with administration of meningococcal C vaccine. Here.


A review of the cases of childhood cancer in Ireland reveal similar figures to other developed counties. Here.

Short reports

Cystic Fibrosis

In routine bronchoscopy after diagnosis in cystic fibrosis, 20% of 25 children were infected with Pseudomonas, some without symptoms. Here.


In a survey of 181 parents attending a clinic, there was widespread confusion about the correct use of antipyretics. Here.

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