A blog post of questions that are calling out to be answered.

Ever looked at the Archimedes section and thought “I wonder what I could write about?” or “I wish they’d look at this?” Here’s the space you were looking for.

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Jamie, a 13-year-old girl with cystic fibrosis (CF), has been referred to the Paediatric Diabetes clinic because of an abnormal oral glucose tolerance test (OGTT) in her recent CF Annual Review. It showed impaired glucose tolerance. Continuous glucose monitoring system (CGMS) over three days showed normal fasting and pre-prandial glucose but frequent post-prandial glucose excursions between 11.1 mmol/l and 16.0 mmol/l. In retrospect, although Jamie’s previous OGTT carried out at Annual Review were normal, her lung function had gradually deteriorated over the past three years. This had been attributed to increasing episodes of infective exacerbations. You wondered for how long Jamie has had abnormal glucose metabolism which had gone undetected in her previous OGTT. more…

A 20 month old presented with 1-day history of temperature, off food and ‘not herself’. Clinical examination showed a slightly irritable child with temperature 38.8⁰C, slightly congested throat and doubtful neck stiffness. An LP shows WCC 2, RCC 0. A diagnosis of viral illness is made, and antibiotics are not commenced.

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